The hypothalamo-neurohypophysial system in streptozotocin-diabetic rats. Ultrastructural evidence for neuronal alterations in the supraoptic and paraventricular nuclei and in the neurohypophysis.

@article{Lincoln1989TheHS,
  title={The hypothalamo-neurohypophysial system in streptozotocin-diabetic rats. Ultrastructural evidence for neuronal alterations in the supraoptic and paraventricular nuclei and in the neurohypophysis.},
  author={J. L. Lincoln and Andrzej Loesch and Geoffrey Burnstock},
  journal={Journal fur Hirnforschung},
  year={1989},
  volume={30 4},
  pages={425-35}
}
The ultrastructure of the hypothalamo-neurohypophysial system of rats was examined 8 weeks after streptozotocin-induction of type I diabetes. These studies provided evidence for numerous neuronal alterations to the hypothalamo-neurohypophysial system in streptozotocin-diabetic rats. Changes were observed in the somata, dendrites and axons of both the supraoptic and paraventricular nuclei as well as in axon profiles in the neurohypophysis. Many of these changes suggest an increased activity of… CONTINUE READING