The hypocholesterolemic and antiatherogenic effects of Cholazol H, a chemically functionalized insoluble fiber with bile acid sequestrant properties in hamsters.

@article{Wilson1998TheHA,
  title={The hypocholesterolemic and antiatherogenic effects of Cholazol H, a chemically functionalized insoluble fiber with bile acid sequestrant properties in hamsters.},
  author={Thomas A. Wilson and Christine A. Romano and J S Liang and Robert James Nicolosi},
  journal={Metabolism: clinical and experimental},
  year={1998},
  volume={47 8},
  pages={
          959-64
        }
}
5 Citations
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Cholestyramine is significantly more potent for reducing serum cholesterol in hypercholesterolemic male SEA quail than is colestipol hydrochloride.
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It is concluded that, while both agents lower cholesterol by a mechanism of increased bile acid excretion, psyllium does not bind bile acids in vivo and lend further support for the concomitant use of these agents for cholesterol-lowering.
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The results indicate that the hamster may be a useful model to examine the effect of different types of protein and the interaction with dietary cholesterol on various plasma lipids and lipoproteins.
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