The hyperbolic equilibrium between insulin sensitivity and secretion.

  • Giovanni Pacini
  • Published 2006 in
    Nutrition, metabolism, and cardiovascular…


AIM The interrelationship between insulin resistance and beta cell secretion has been qualitatively described by a hyperbolic function and quantitatively by the disposition index. The concepts behind these assumptions are however still controversial and this review aims to briefly recall the main aspects of the hyperbolic paradigm in terms of mathematical… (More)


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