The hungry fetus? Role of leptin as a nutritional signal before birth.

  title={The hungry fetus? Role of leptin as a nutritional signal before birth.},
  author={Alison J Forhead and Abigail L Fowden},
  journal={The Journal of physiology},
  volume={587 Pt 6},
In adult animals, leptin is an adipose-derived hormone that is important primarily in the regulation of energy balance during short- and long-term changes in nutritional state. Expression of leptin and its receptors is widespread in fetal and placental tissues, although the role of leptin as a nutritional signal in utero is unclear. Before birth, leptin concentration correlates with several indices of fetal growth, and may be an endocrine marker of fetal size and energy stores in the control of… CONTINUE READING
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