The human trithorax protein hASH2 functions as an oncoprotein.

Abstract

Regulation of chromatin is an important aspect of controlling promoter activity and gene expression. Posttranslational modifications of core histones allow proteins associated with gene transcription to access chromatin. Closely associated with promoters of actively transcribed genes, trimethylation of histone H3 at lysine 4 (H3K4me3) is a core histone mark… (More)
DOI: 10.1158/0008-5472.CAN-07-3158

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@article{LscherFirzlaff2008TheHT, title={The human trithorax protein hASH2 functions as an oncoprotein.}, author={Juliane M L{\"{u}scher-Firzlaff and Isabella Gawlista and J{\"{o}rg Vervoorts and Karsten Kapelle and Till Braunschweig and Gesa Walsemann and Chantal Rodgarkia-Schamberger and Henning Schuchlautz and Stephan Dreschers and Elisabeth Kremmer and Richard Lilischkis and Christa Cerni and Axel Wellmann and Bernhard L{\"{u}scher}, journal={Cancer research}, year={2008}, volume={68 3}, pages={749-58} }