The human sialyltransferase family.

@article{HarduinLepers2001TheHS,
  title={The human sialyltransferase family.},
  author={Anne Harduin-Lepers and V Vallejo-Ruiz and Marie-Ange Krzewinski-Recchi and B{\'e}n{\'e}dicte Samyn-Petit and Sylvain Julien and Philippe Delannoy},
  journal={Biochimie},
  year={2001},
  volume={83 8},
  pages={727-37}
}
The human genome encodes probably more than 20 different sialyltransferases involved in the biosynthesis of sialylated glycoproteins and glycolipids but to date only 15 different human sialyltransferase cDNAs have been cloned and characterized. Each of the sialyltransferase genes is differentially expressed in a tissue-, cell type-, and stage-specific manner to regulate the sialylation pattern of cells. These enzymes differ in their substrate specificity, tissue distribution and various… CONTINUE READING
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