The human pim-1 gene is not directly activated by the translocation (6;9) in acute nonlymphocytic leukemia.

@article{Lindern1989TheHP,
  title={The human pim-1 gene is not directly activated by the translocation (6;9) in acute nonlymphocytic leukemia.},
  author={Marieke von Lindern and Ton van Agthoven and Anne M Hagemeijer and Henk J Adriaansen and Gerard C. Grosveld},
  journal={Oncogene},
  year={1989},
  volume={4 1},
  pages={75-9}
}
In Acute Nonlymphocytic Leukemia (ANLL) specified by a reciprocal translocation (6;9), defined clinical and morphological features are observed. This suggests that genes located near the breakpoints of the translocation chromosomes are involved in the generation of this subtype of leukemia. The human pim-1 gene has been mapped near the t(6;9) breakpoint on chromosome 6. Using somatic cell hybrids we demonstrated that the pim-1 gene remains on chromosome 6. We investigated whether pim-1 plays a… CONTINUE READING

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Chromosomes, Human, Pair 6Chromosome involved in cytogenetic abnormalityt(6;9)
The human pim-1 gene has been mapped near the t(6;9 ) breakpoint on chromosome 6 .
In Acute Nonlymphocytic Leukemia ( ANLL ) specified by a reciprocal translocation ( 6;9 ) , defined clinical and morphological features are observed .
In Acute Nonlymphocytic Leukemia ( ANLL ) specified by a reciprocal translocation ( 6;9 ) , defined clinical and morphological features are observed .
In Acute Nonlymphocytic Leukemia ( ANLL ) specified by a reciprocal translocation ( 6;9 ) , defined clinical and morphological features are observed .
In Acute Nonlymphocytic Leukemia ( ANLL ) specified by a reciprocal translocation ( 6;9 ) , defined clinical and morphological features are observed .
In Acute Nonlymphocytic Leukemia ( ANLL ) specified by a reciprocal translocation ( 6;9 ) , defined clinical and morphological features are observed .
In Acute Nonlymphocytic Leukemia ( ANLL ) specified by a reciprocal translocation ( 6;9 ) , defined clinical and morphological features are observed .
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