The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters.

@article{Roermund2008TheHP,
  title={The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters.},
  author={Carlo W T van Roermund and Wouter F. Visser and Lodewijk van Ijlst and Arno G van Cruchten and Maxim Boek and Wim Kulik and H. R. Waterham and Ronald J. A. Wanders},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2008},
  volume={22 12},
  pages={4201-8}
}
Peroxisomes play a major role in human cellular lipid metabolism, including the beta-oxidation of fatty acids. The most frequent peroxisomal disorder is X-linked adrenoleukodystrophy (X-ALD), which is caused by mutations in the ABCD1 gene. The protein involved, called ABCD1, or alternatively ALDP, is a member of the ATP-binding-cassette (ABC) transporter… CONTINUE READING