The human peripheral lymph node vascular addressin. An inducible endothelial antigen involved in lymphocyte homing.

@article{Michie1993TheHP,
  title={The human peripheral lymph node vascular addressin. An inducible endothelial antigen involved in lymphocyte homing.},
  author={Sara A. Michie and Philip R. Streeter and P A Bolt and Eugene C. Butcher and Louis J. Picker},
  journal={The American journal of pathology},
  year={1993},
  volume={143 6},
  pages={1688-98}
}
The extravasation of blood-borne lymphocytes into organized lymphoid tissues and sites of chronic inflammation is directed in part by interactions of lymphocyte surface adhesion molecules, known as homing receptors, with tissue-selective endothelial ligands called vascular addressins. In mice and humans, lymphocyte L-selectin and the peripheral lymph node addressin (PNAd) form a homing receptor-endothelial ligand pair involved in lymphocyte traffic to peripheral lymph node (PLN). We have… CONTINUE READING
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