The human parasite Loa loa in cytokine and cytokine receptor gene knock out BALB/c mice: survival, development and localization

@inproceedings{Tendongfor2011TheHP,
  title={The human parasite Loa loa in cytokine and cytokine receptor gene knock out BALB/c mice: survival, development and localization},
  author={Nicholas Tendongfor and Samuel Wanji and Julius C Ngwa and Mathias Eyong Esum and Sabine Specht and Peter AI Enyong and Klaus Ingo Matthaei and Achim Hoerauf},
  booktitle={Parasites & Vectors},
  year={2011}
}
Immunological mechanisms involved in the survival and development of human filarial species in the vertebrate host are poorly known due to the lack of suitable experimental models. In order to understand the role of cytokines in the survival and development of filarial larvae in the vertebrate host, we infected different strains of BALB/c mice deficient in a number of cytokine or cytokine receptor genes with Loa loa. The survival and development of larvae were monitored. BALB/c mice genetically… CONTINUE READING
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