The human papillomavirus 16 E2 protein is stabilised in S phase.

@article{Johansson2009TheHP,
  title={The human papillomavirus 16 E2 protein is stabilised in S phase.},
  author={Cecilia Johansson and Sheila V Graham and Edward S Dornan and Iain M. Morgan},
  journal={Virology},
  year={2009},
  volume={394 2},
  pages={194-9}
}
The human papillomavirus 16 E2 protein regulates transcription from, and replication of, the viral genome and is also required for segregation of the viral genome via interaction with mitotic bodies. To regulate DNA replication E2 interacts with sequences around the origin of replication and recruits the viral helicase E1 via a protein-protein interaction, which then initiates viral genome replication. The replication role of E2 must originally function in a host cell S phase. In this report… CONTINUE READING

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