The human oral metaproteome reveals potential biomarkers for caries disease.

  title={The human oral metaproteome reveals potential biomarkers for caries disease.},
  author={Pedro Belda-Ferre and James C. Williamson and {\'A}urea Sim{\'o}n-Soro and Alejandro Artacho and Ole N Jensen and Alejandro Mira},
  volume={15 20},
Tooth decay is considered the most prevalent human disease worldwide. We present the first metaproteomic study of the oral biofilm, using different mass spectrometry approaches that have allowed us to quantify individual peptides in healthy and caries-bearing individuals. A total of 7771 bacterial and 853 human proteins were identified in 17 individuals, which provide the first available protein repertoire of human dental plaque. Actinomyces and Coryneybacterium represent a large proportion of… CONTINUE READING
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