The human muscle proteome in aging.

@article{Gelfi2006TheHM,
  title={The human muscle proteome in aging.},
  author={Cecilia Gelfi and Agnese Vigan{\`o} and M. Ripamonti and Alessandro Pontoglio and Shajna Begum and Maria Antonietta Pellegrino and Bruno Grassi and Roberto Bottinelli and ' Robin Wait and Paolo Cerretelli},
  journal={Journal of proteome research},
  year={2006},
  volume={5 6},
  pages={
          1344-53
        }
}
The aim of the present study was to assess age-dependent changes of proteins in the vastus lateralis muscle of physically active elderly and young subjects by a combination of two-dimensional difference gel electrophoresis, SDS-PAGE and ESI-MS/MS. The differences observed in the elderly group included down-regulation of regulatory myosin light chains, particularly the phosphorylated isoforms, a higher proportion of myosin heavy chain isoforms 1 and 2A, and enhanced oxidative and reduced… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 78 CITATIONS, ESTIMATED 61% COVERAGE

127 Citations

01020'08'11'14'17
Citations per Year
Semantic Scholar estimates that this publication has 127 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…