The human multidrug resistance protein 2 gene: functional characterization of the 5'-flanking region and expression in hepatic cells.

Abstract

The human multidrug resistance protein 2 (MRP2), also termed as the canalicular multispecific organic anion transporter (cMOAT), is a member of the adenosine triphosphate-binding cassette transporter superfamily. In the liver, MRP2 mediates the multispecific efflux of various types of organic anions, including glucuronate, sulfate, and glutathione… (More)

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