The human locus coeruleus: computer reconstruction of cellular distribution.

  title={The human locus coeruleus: computer reconstruction of cellular distribution.},
  author={Dwight C. German and B. Preilowski. Th. Rasmussen'V. S. Rossiter'R. E. Sau Walker and Kebreten F. Manaye and Wade K. Smith and D. J. Woodward and Alison J. North},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={8 5},
Quantitative neuroanatomical techniques were developed to map the distribution of norepinephrine-containing locus coeruleus (LC) neurons in the adult human brain. These neurons reside in the dorsolateral pontine tegmentum and are identifiable by their neuromelanin pigment content. Five brains, ranging in age from 60 to 104 years, were examined. Outlines of coronal or sagittal sections containing the LC were entered into a computer along with the location of each cell, certain neuroanatomical… CONTINUE READING


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