The human immunodeficiency virus type 1 regulatory protein Tat inhibits interferon-induced iNos activity in a murine macrophage cell line.

Abstract

Human immunodeficiency virus type 1 (HIV-1) infection is frequently associated with concurrent infection by opportunistic pathogens, against which production of nitric oxide by host macrophages provides a first line of defence. We have investigated whether regulatory HIV-1 proteins, such as Tat, can modulate the activity of the inducible nitric oxide… (More)

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@article{Barton1996TheHI, title={The human immunodeficiency virus type 1 regulatory protein Tat inhibits interferon-induced iNos activity in a murine macrophage cell line.}, author={C Howard Barton and Thelma E Biggs and Trevor R Mee and D. A. Mann}, journal={The Journal of general virology}, year={1996}, volume={77 ( Pt 8)}, pages={1643-7} }