The human hexokinase II gene promoter: functional characterization and detection of variants among patients with NIDDM

Abstract

Hexokinase II (HKII) plays an important role in facilitating glucose uptake by skeletal muscle, heart, and adipose tissue in response to insulin. We have cloned and sequenced the proximal promoter region of the human HKII gene, determined the transcription start sites and screened the 2.0 kb of the proximal 5 ′ flanking region for variants in non-insulin… (More)
DOI: 10.1007/s001250050850

Topics

3 Figures and Tables

Slides referencing similar topics