The human gut microbiome as a screening tool for colorectal cancer.

  title={The human gut microbiome as a screening tool for colorectal cancer.},
  author={Joseph P. Zackular and Mary A M Rogers and Mack T Ruffin and Patrick D. Schloss},
  journal={Cancer prevention research},
  volume={7 11},
Recent studies have suggested that the gut microbiome may be an important factor in the development of colorectal cancer. Abnormalities in the gut microbiome have been reported in patients with colorectal cancer; however, this microbial community has not been explored as a potential screen for early-stage disease. We characterized the gut microbiome in patients from three clinical groups representing the stages of colorectal cancer development: healthy, adenoma, and carcinoma. Analysis of the… CONTINUE READING
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