The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p

@article{Jay1997TheHG,
  title={The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p},
  author={Philippe Jay and J L Berge-lefranc and C Marsollier and Catherine M{\'e}jean and Sylvie Taviaux and Philippe Berta},
  journal={Oncogene},
  year={1997},
  volume={14},
  pages={1753-1757}
}
Complementary DNA encoding the human CYR61 protein was isolated from human embryonic tissues and mapped to chromosome 1p22-p31. We show that CYR61 encodes a 381 amino acid protein rich in cysteine and proline residues that is strongly conserved with the mouse homologue. Sequence analysis reveals the presence of several distinct protein domains which confer a mosaic structure to this protein and makes human CYR61 a member of a recently described growth regulator family that includes several… CONTINUE READING