The human genome-wide distribution of DNA palindromes

  title={The human genome-wide distribution of DNA palindromes},
  author={Le N Lu and Hui Jia and Peter Dr{\"o}ge and Jinming Li},
  journal={Functional & Integrative Genomics},
In this work, we performed a systematic study of perfect and nonspacer palindromes present in human genomic DNA, and we investigated palindrome distribution over the entire human genome and over the functional regions such as the exon, intron, intergenic, and upstream regions (2,000 bp upstream from translational start site). We found that 24 palindrome-abundant intervals are mostly located on G-bands, which condense early, replicate late, and are relatively A+T rich. In general, palindromes… CONTINUE READING