The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs.

@article{Song1993TheHG,
  title={The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs.},
  author={I Song and David R Brown and Rodney N Wiltshire and Ira Gantz and Jeffrey M. Trent and Takahiro Yamada},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 19},
  pages={9085-9}
}
Gastrin and its carboxyl-terminal homolog cholecystokinin (CCK) exert a variety of biological actions in the brain and gastrointestinal tract that are mediated in part through one or more G protein-coupled receptors which exhibit similar affinity for both peptides. Genomic clones encoding a human gastrin/CCKB receptor were isolated by screening a human EMBL phage library with a partial-length DNA fragment which was based on the nucleotide sequence of the canine gastrin receptor. The gene… CONTINUE READING
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