The human cytomegalovirus.

@article{Landolfo2003TheHC,
  title={The human cytomegalovirus.},
  author={Santo Landolfo and Marisa Gariglio and Giorgio Gribaudo and David Lembo},
  journal={Pharmacology & therapeutics},
  year={2003},
  volume={98 3},
  pages={
          269-97
        }
}
Human cytomegalovirus (HCMV), a betaherpesvirus, represents the major infectious cause of birth defects, as well as an important pathogen for immunocompromised individuals. The viral nucleocapsid containing a linear double-stranded DNA of 230 kb is surrounded by a proteinaceous tegument, which is itself enclosed by a loosely applied lipid bilayer. Expression of the HCMV genome is controlled by a cascade of transcriptional events that leads to the synthesis of three categories of viral proteins… CONTINUE READING
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