The human cytokine TSLP triggers a cell-autonomous dendritic cell migration in confined environments.

Abstract

Dendritic cells (DCs) need to migrate in the interstitial environment of peripheral tissues to reach secondary lymphoid organs and initiate a suitable immune response. Whether and how inflamed tissues instruct DCs to emigrate is not fully understood. In this study, we report the unexpected finding that the epithelial-derived cytokine TSLP triggers… (More)
DOI: 10.1182/blood-2010-12-323089

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