The human Y chromosome: a masculine chromosome.

  title={The human Y chromosome: a masculine chromosome.},
  author={Michiel J. Noordam and Sjoerd Repping},
  journal={Current opinion in genetics & development},
  volume={16 3},
Once considered to be a genetic wasteland of no scientific interest beyond sex determination, the human Y chromosome has made a significant comeback in the past few decades and is currently implicated in multiple diseases, including spermatogenic failure - absent or very low levels of sperm production. The Y chromosome contains over one hundred testis-specific transcripts, and several deletions have been described that remove some of these transcripts, thereby causing spermatogenic failure… CONTINUE READING

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