The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.

@article{Nagy2009TheHS,
  title={The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.},
  author={Zita Nagy and Anne Riss and Christophe Romier and Xavier le Guezennec and Ashok R. Dongr{\'e} and Meritxell Orpinell and Jiahuai Han and Henk Stunnenberg and Laszlo Tora},
  journal={Molecular and cellular biology},
  year={2009},
  volume={29 6},
  pages={1649-60}
}
One of the central questions in eukaryotic transcription is how activators can transmit their signal to stimulate gene expression in the context of chromatin. The multisubunit SAGA coactivator complex has both histone acetyltransferase and deubiquitination activities and remodels chromatin to allow transcription. Whether and how SAGA is able to regulate transcription at specific loci is poorly understood. Using mass spectrometry, immunoprecipitation, and Western blot analysis, we have… CONTINUE READING
24 Citations
60 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 60 references

Similar Papers

Loading similar papers…