The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation

@article{Jouhilahti2016TheHP,
  title={The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation},
  author={Eeva-Mari Jouhilahti and Elo Madissoon and Lise Vesterlund and Virpi T{\"o}h{\"o}nen and Kaarel Krjut{\vs}kov and {\'A}lvaro Plaza Reyes and Sophie Petropoulos and Robert Månsson and Sten Linnarsson and Thomas R. B{\"u}rglin and Fredrik Lanner and Outi Hovatta and Shintaro Katayama and Juha Kere},
  journal={Development (Cambridge, England)},
  year={2016},
  volume={143},
  pages={3459 - 3469}
}
Leucine twenty homeobox (LEUTX) is a paired (PRD)-like homeobox gene that is expressed almost exclusively in human embryos during preimplantation development. We previously identified a novel transcription start site for the predicted human LEUTX gene based on the transcriptional analysis of human preimplantation embryos. The novel variant encodes a protein with a complete homeodomain. Here, we provide a detailed description of the molecular cloning of the complete homeodomain-containing LEUTX… 
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Transient DUX4 expression induces blastomere-like expression program that is marked by SLC34A2
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Dynamic Molecular Evolution of Mammalian Homeobox Genes: Duplication, Loss, Divergence and Gene Conversion Sculpt PRD Class Repertoires
TLDR
Comparisons of ETCHbox genes of 34 mammalian species reveal dynamic patterns of gene loss and tandem duplication, including the presence of a large tandem array of LEUTX loci in the genome of the European rabbit (Oryctolagus cuniculus).
The Dynamic Changes of Transcription Factors During the Development Processes of Human Biparental and Uniparental Embryos
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This work systematically studied the expression profiles of transcription factors in early embryonic development and revealed the dynamic changes of TFs in human biparental and uniparental embryogenesis by single-cell RNA sequencing (scRNA-seq).
Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development.
Transient DUX4 expression in human embryonic stem cells induces blastomere-like expression program that is marked by SLC34A2.
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