The host response to sepsis and developmental impact.

  title={The host response to sepsis and developmental impact.},
  author={James L Wynn and Timothy T Cornell and Hector R Wong and Thomas P. Shanley and Derek S. Wheeler},
  volume={125 5},
Invasion of the human by a pathogen necessitates an immune response to control and eradicate the microorganism. When this response is inadequately regulated, systemic manifestations can result in physiologic changes described as "sepsis." Recognition, diagnosis, and management of sepsis remain among the greatest challenges shared by the fields of neonatology and pediatric critical care medicine. Sepsis remains among the leading causes of death in both developed and underdeveloped countries and… CONTINUE READING
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