The host immune response to Clostridium difficile.

  title={The host immune response to Clostridium difficile.},
  author={Ciaran Kelly and Lorraine Kyne},
  journal={Journal of medical microbiology},
  volume={60 Pt 8},
Clostridium difficile is the most common cause of nosocomial bacterial diarrhoea in the Western world. Diarrhoea and colitis are caused by the actions of toxins A and B released by pathogenic strains of C. difficile. Adaptive immune responses to these toxins influence the outcomes of C. difficile infection (CDI). Symptomless carriers of toxinogenic C. difficile and those with a single episode of CDI without recurrence show more robust antitoxin immune responses than those with symptomatic and… CONTINUE READING


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