The hormone-sensitive lipase gene is transcribed from at least five alternative first exons in mouse adipose tissue

@article{Laurin2000TheHL,
  title={The hormone-sensitive lipase gene is transcribed from at least five alternative first exons in mouse adipose tissue},
  author={N. Laurin and S. Wang and G. Mitchell},
  journal={Mammalian Genome},
  year={2000},
  volume={11},
  pages={972-978}
}
Abstract. Hormone-sensitive lipase (HSL) mediates triglyceride hydrolysis in adipocytes, in which its expression varies with physiological stress and is controlled posttranslationally and transcriptionally. We sequenced the mouse HSL gene for 8.2 kb upstream of the translation start codon and studied the steady-state HSL mRNA levels in mouse adipose tissue. In 50 clones derived from primer extension and PCR of mouse adipose cDNA, we found five distinct 5′ extremities that correspond to distinct… Expand
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