The hormonal regulation of gene expression of glial markers: glutamine synthetase and glycerol phosphate dehydrogenase in primary cultures of rat brain and in C6 cell line.

Abstract

Increases in the mRNA levels of two neuroglial markers, glutamine synthetase (EC 6.3.1.2; GS) and glycerolphosphate dehydrogenase (EC 1.1.1.8; GPDH), were observed in hydrocortisone-treated cultures of astrocytes and oligodendrocytes, respectively, and in C6 cells by Northern blot analysis and in situ hybridization. In vitro transcription assays… (More)

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@article{Kumar1986TheHR, title={The hormonal regulation of gene expression of glial markers: glutamine synthetase and glycerol phosphate dehydrogenase in primary cultures of rat brain and in C6 cell line.}, author={S Kumar and Eleri Holmes and Sheila A. Scully and Bruce W. Birren and R. H. Wilson and Jean de Vellis}, journal={Journal of neuroscience research}, year={1986}, volume={16 1}, pages={251-64} }