The honeymoon phase: intersection of metabolism and immunology

  title={The honeymoon phase: intersection of metabolism and immunology},
  author={H. Aly and P. Gottlieb},
  journal={Current Opinion in Endocrinology, Diabetes and Obesity},
  • H. Aly, P. Gottlieb
  • Published 2009
  • Medicine
  • Current Opinion in Endocrinology, Diabetes and Obesity
  • Purpose of reviewEven though the honeymoon phase in type 1 diabetes mellitus has been well known, its underlying pathogenic mechanisms remain poorly described. The common explanation that it occurs due to ‘β-cell rest’ on initiation of insulin therapy seems inadequate based on recent observations and studies and its underlying immunological aspects overlooked. Recent findingsIn this article, we will review the metabolic and immunological aspects of the honeymoon phase and we will present our… CONTINUE READING
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