The homeodomain protein Cdx2 regulates lactase gene promoter activity during enterocyte differentiation.

@article{Fang2000TheHP,
  title={The homeodomain protein Cdx2 regulates lactase gene promoter activity during enterocyte differentiation.},
  author={Rixun Fang and Nilda A. Santiago and Lynne C. Olds and Eric Sibley},
  journal={Gastroenterology},
  year={2000},
  volume={118 1},
  pages={115-27}
}
BACKGROUND & AIMS Lactase is the intestinal disaccharidase responsible for digestion of lactose, the predominant carbohydrate in milk. Transcription of the lactase gene is activated during enterocyte differentiation. We have characterized the interaction between the lactase promoter and Cdx2, a homeodomain protein involved in regulating intestinal development and differentiation. METHODS Nuclear protein bound to the lactase gene cis element, CE-LPH1, was analyzed by electrophoretic mobility… CONTINUE READING
36 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

Similar Papers

Loading similar papers…