The homeobox gene Six3 is a potential regulator of anterior segment formation in the chick eye.

@article{Hsieh2002TheHG,
  title={The homeobox gene Six3 is a potential regulator of anterior segment formation in the chick eye.},
  author={Yi-Wen Hsieh and Xiang-mei Zhang and Eddie Lin and Guillermo Oliver and Xian-jie Yang},
  journal={Developmental biology},
  year={2002},
  volume={248 2},
  pages={265-80}
}
The anterior segment of the vertebrate eye consists of highly organized and specialized ocular tissues critical for normal vision. The periocular mesenchyme, originating from the neural crest, contributes extensively to the anterior segment. During chick eye morphogenesis, the homeobox gene Six3 is expressed in a subset of periocular mesenchymal cells and in differentiating anterior segment tissues. Retrovirus-mediated misexpression of Six3 causes eye anterior segment malformation, including… CONTINUE READING

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