The history of the tetracyclines

@article{Nelson2011TheHO,
  title={The history of the tetracyclines},
  author={Mark L. Nelson and Stuart B. Levy},
  journal={Annals of the New York Academy of Sciences},
  year={2011},
  volume={1241}
}
  • M. Nelson, S. Levy
  • Published 1 December 2011
  • Biology
  • Annals of the New York Academy of Sciences
The history of the tetracyclines involves the collective contributions of thousands of dedicated researchers, scientists, clinicians, and business executives over the course of more than 60 years. Discovered as natural products from actinomycetes soil bacteria, the tetracyclines were first reported in the scientific literature in 1948. They were noted for their broad spectrum antibacterial activity and were commercialized with clinical success beginning in the late 1940s to the early 1950s. The… 

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