The history and market impact of CRISPR RNA-guided nucleases.

Abstract

The interface between viruses and their hosts' are hot spots for biological and biotechnological innovation. Bacteria use restriction endonucleases to destroy invading DNA, and industry has exploited these enzymes for molecular cut-and-paste reactions that are central to many recombinant DNA technologies. Today, another class of nucleases central to… (More)
DOI: 10.1016/j.coviro.2015.03.011

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