The historical role and contemporary use of corticosteroids in inflammatory bowel disease.

@article{Dorrington2020TheHR,
  title={The historical role and contemporary use of corticosteroids in inflammatory bowel disease.},
  author={Alexander M Dorrington and Christian Philipp Selinger and Gareth C Parkes and Melissa Smith and Richard C G Pollok and Tim Raine},
  journal={Journal of Crohn's \& colitis},
  year={2020}
}
The use of corticosteroids to treat patients with inflammatory bowel disease (IBD) has been the bedrock of IBD therapeutics since the pioneering work of Truelove and Witts in the UK in the 1950s and subsequent large cohort studies in the US and Europe. Nevertheless, whilst effective for induction of remission, these agents do not maintain remission and are associated with a long list of recognised side effects, including a risk of increased mortality. With the arrival of an increasing number of… 
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