• DOI:10.1111/j.1365-2184.2006.00377.x
Corpus ID: 16515437

The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential

@article{Mahdi2006TheHA,
  title={The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential},
  author={J. G. Mahdi and A. J. Mahdi and I. D. Bowen},
  journal={Cell Proliferation},
  year={2006},
  volume={39}
}

J. G. Mahdi, A. J. Mahdi, +1 author I. D. Bowen

Published 2006

Biology, Medicine

Cell Proliferation

Abstract.  For several millennia, the willow tree and salicin have been associated with salicylic acid, the key precursor molecule that has contributed to the discovery of acetylsalicylic acid, traded as aspirin. These molecules have been shown to possess phyto‐ and chemotherapeutic activities as analgesic drugs. In recent decades, aspirin has become the focus of extensive investigation into antiproliferative and anticancer activities. The historical steps that led to the discovery of aspirin… CONTINUE READING

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