The histology of anal skin tags in Crohn's disease: An aid to confirmation of the diagnosis

  title={The histology of anal skin tags in Crohn's disease: An aid to confirmation of the diagnosis},
  author={B. A. Taylor and G. T. Williams and L. E. Hughes and Jonathan Rhodes},
  journal={International Journal of Colorectal Disease},
We have investigated excision biopsy of anal skin tags as an adjunct to rectal biopsy in the diagnosis of Crohn's disease. Twenty-six patients with proven Crohn's disease of the large and/or small bowel were studied. All had perianal skin tags removed under local anaesthesia as outpatients, when rectal biopsies were also obtained. Three sections from each skin tag and three from each rectal biopsy were examined for granulomas. The rectal biopsies were also examined for changes ‘suggestive’ of… 
Perianal skin tags in a patient with Crohn disease and a subclinical rectal stricture.
A 21-year-old female-to-male transgender individual with a history of Crohn disease presented with enlarging perianal papules that initially were misdiagnosed as condyloma acuminatum and later revealed the presence of a rectal stricture that was then dilated.
Anal skin tags in inflammatory bowel disease: New observations and a clinical review
These observations support the diagnostic significance of AST heralding the diagnosis of CD when they are discovered on physical exam, especially in young people with diarrhea, abdominal pain, and/or growth retardation.
Diagnosis and treatment of perianal Crohn disease: NASPGHAN clinical report and consensus statement.
The etiology, diagnosis, evaluation, and treatment of perianal Crohn disease is reviewed and discussed, with a focus on the treatment of PCD.
Nonfistulizing perianal Crohn's disease: clinical features, epidemiology, and treatment.
After reviewing the classification, clinical features, and epidemiology of each type of nonfistulizing perianal lesion (ulceration, stricture, skin tags, and anal cancer), the efficacy of medical treatment and surgery is discussed.
Metastatic Cutaneous Crohn's Disease of the Nipple: Report of a Case
Histopathologic examination following excision of the fistulas and total duct excision showed well-defined granulomas containing multinucleated giant cells characteristic of extraintestinal Crohn's disease.
Anorectal Crohn’s Disease
Desired outcomes of therapy for anorectal Crohn’s disease should include complete healing when possible, maintenance of rectal function and continence, elimination of sepsis, and overall improvement in quality of life.
Anal skin tag - an unusual presenting feature of food protein-induced allergic proctocolitis in a neonate.
Clinicians should consider food protein-induced allergic proctocolitis in their differential diagnosis in a neonate presenting with blood in stools and anal skin tag, according to literature reported on this case.
Genital swelling in an adolescent patient
A 16-year-old-boy was referred to the Department of Pediatrics, University of Chieti, Italy, with a 2-month history of persistent, asymptomatic, painless penile and scrotal swelling and results of repeated serological tests for syphilis or other venereal diseases were negative.
Management of Perianal Skin Tags
The incidence of skin tags in Crohn’s disease (CD) is likely underreported as few studies consider them to be as significant as other perianal manifestations such as fissure or fistula and may not


Rectal biopsy in patients with Crohn's disease. Normal mucosa on sigmoidoscopic examination.
Of 99 patients with Crohn's disease whose rectal segment appeared normal on sigmoidoscopy, there was histologic inflammation in 45% and features characteristic of Crohn's disease in 30% of rectal
Clinical usefulness of rectal biopsy in Crohn's disease
Crohn's disease of the anal region.
The object of this paper is to present the clinical features, pathology, and subsequent course of this last group of patients who presented with anal lesions which suggested Crohn's disease both clinically and histologically, who had at the time neither clinical nor radiological evidence of intestinal pathology.
The incidence of granulomas in serial sections of rectal biopsies from patients with Crohn's disease.
Serial sections were cut through the entire thickness of rectal biopsies from 39 patients with Crohn's disease, showing that cutting a limited number of sections is inadequate and that only total serial sectioning will ensure that granulomas are not overlooked.
Surgical Pathology and Management of Anorectal Crohn's Disease
  • L. Hughes
  • Medicine
    Journal of the Royal Society of Medicine
  • 1978
The anorectal manifestations of Crohn's disease comprise a complex and heterogeneous group of conditions which fall into two main categories: primary lesions of the active disease process and
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  • Engineering
    The Ulster Medical Journal
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THERE is no doubt that this book fills an empty slot in the library of anaesthesia. It enters, however timidly, the realm of the mechanical engineer, and in future editions this trend is to be
Perianal lesions in Crohn's disease.