The histamine H3 receptor as a therapeutic drug target for CNS disorders.

Abstract

The histamine H3 receptor plays a regulatory role in the pre-synaptic release of histamine and other neurotransmitters, making it an attractive target for CNS indications including cognitive disorders, narcolepsy, ADHD and pain. As more and more H3 antagonists/H3 inverse agonists progress through the clinic, knowledge is gained to define the profile of the… (More)
DOI: 10.1016/j.drudis.2009.02.011

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Cite this paper

@article{Gemkow2009TheHH, title={The histamine H3 receptor as a therapeutic drug target for CNS disorders.}, author={Mark J Gemkow and Adam J Davenport and Silke Harich and Bart A Ellenbroek and Andrea M Cesura and David Hallett}, journal={Drug discovery today}, year={2009}, volume={14 9-10}, pages={509-15} }