The hippocampus and depression.

  title={The hippocampus and depression.},
  author={Yvette I. Sheline and B L Mittler and Mark A. Mintun},
  journal={European psychiatry : the journal of the Association of European Psychiatrists},
  volume={17 Suppl 3},
The effect of depression on the hippocampus has become the focus of a number of structural and functional neuroimaging studies. In the past two decades, advances in neuroimaging techniques now allow the examination of subtle changes in both regional structure and function that are associated with the pathophysiology of depression. Many studies using 3-dimensional magnetic resonance imaging (MRI) volumetric measurement have reported decreases in hippocampal volume among depressed subjects… CONTINUE READING