The hippocampal dentate gyrus is essential for generating contextual memories of fear and drug-induced reward

@article{HernndezRabaza2008TheHD,
  title={The hippocampal dentate gyrus is essential for generating contextual memories of fear and drug-induced reward},
  author={Vicente Hern{\'a}ndez-Rabaza and Lourdes Hontecillas-Prieto and Clara Vel{\'a}zquez-S{\'a}nchez and Antonio Ferragud and Juan Jose Canales},
  journal={Neurobiology of Learning and Memory},
  year={2008},
  volume={90},
  pages={553-559}
}
The hippocampus is believed to play a role in processing information relative to the context in which emotionally salient experiences occur but evidence on the specific contribution of the hippocampal dentate gyrus (DG) to these processes is limited. Here, we have used two classical behavioral paradigms to study the participation of the dorsal DG in context-conditioned reward and context-conditioned fear. Rats received intra-hippocampal vehicle or colchicine injections (4 microg/microl solution… CONTINUE READING

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