The highest affinity binding site of small protein B on transfer messenger RNA is outside the tRNA domain.

Abstract

Eubacterial ribosomes stalled on defective mRNAs are released through a mechanism referred to as trans-translation, depending on the coordinated actions of small protein B (SmpB) and transfer messenger RNA (tmRNA). A series of tmRNA variants with deletions in each structural domain were produced. Their structures were monitored by enzymatic and chemical… (More)
DOI: 10.1261/rna.1185808

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