The high serum monocyte chemoattractant protein-1 in obesity is influenced by high parathyroid hormone and not adiposity.

@article{Sukumar2011TheHS,
  title={The high serum monocyte chemoattractant protein-1 in obesity is influenced by high parathyroid hormone and not adiposity.},
  author={Deeptha Sukumar and Nicola C Partridge and Xiuzhi Wang and Sue A Shapses},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2011},
  volume={96 6},
  pages={1852-8}
}
CONTEXT Chronic high levels of PTH may be associated with up-regulation of proteases and cytokines. Monocyte chemoattractant protein-1 (MCP-1) is an inflammatory cytokine, produced predominantly by macrophages and endothelial cells, and is expressed in adipose tissue. More recently it has been shown that PTH administration increases MCP-1 expression in osteoblasts. OBJECTIVES Because both PTH and MCP-1 levels are higher in obesity, the goal was to determine whether the high MCP-1 occurs only… CONTINUE READING
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