The high-mobility group I-Y transcription factor is involved in cerebral ischemia and modulates the expression of angiogenic proteins.

@article{Cams2014TheHG,
  title={The high-mobility group I-Y transcription factor is involved in cerebral ischemia and modulates the expression of angiogenic proteins.},
  author={Susanna Cam{\'o}s and Carme Gubern and M{\'o}nica Sobrado and Roc{\'i}o de Iriarte Rodr{\'i}guez and V{\'i}ctor G. Romera and Mar{\'i}a {\'A}ngeles Moro and Ignacio Lizasoain and Joaqu{\'i}n Serena and Judith Mallolas and Mar Castellanos},
  journal={Neuroscience},
  year={2014},
  volume={269},
  pages={112-30}
}
The present study aims to identify transcription factors (TFs) contributing to angiogenesis, a mechanism involved in giving plasticity to the brain, as potential therapeutic targets after cerebral ischemia. The promoter sequences from candidate genes involved in angiogenesis were submitted to a comparative analysis by bioinformatics software. High-mobility group I-Y protein (HMGIY) TF characterization in a rat permanent focal cerebral ischemia model was performed by quantitative real time… CONTINUE READING