The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3.

@article{Suzuki2009TheHO,
  title={The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3.},
  author={Hitomi Suzuki and Aiko Sada and Shosei Yoshida and Yumiko Saga},
  journal={Developmental biology},
  year={2009},
  volume={336 2},
  pages={222-31}
}
Spermatogonial stem cells (SSCs) reside in undifferentiated type-A spermatogonia and contribute to continuous spermatogenesis by maintaining the balance between self-renewal and differentiation, thereby meeting the biological demand in the testis. Spermatogonia have to date been characterized principally through their morphology, but we herein report the detailed characterization of undifferentiated spermatogonia in mouse testes based on their gene expression profiles in combination with… CONTINUE READING

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