The herpesvirus proteases as targets for antiviral chemotherapy.

  title={The herpesvirus proteases as targets for antiviral chemotherapy.},
  author={Lloyd H Waxman and Paul L. Darke},
  journal={Antiviral chemistry & chemotherapy},
  volume={11 1},
Viruses of the family Herpesviridae are responsible for a diverse set of human diseases. The available treatments are largely ineffective, with the exception of a few drugs for treatment of herpes simplex virus (HSV) infections. For several members of this DNA virus family, advances have been made recently in the biochemistry and structural biology of the essential viral protease, revealing common features that may be possible to exploit in the development of a new class of anti-herpesvirus… CONTINUE READING
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