The hepatitis C virus non-structural protein NS5A alters the trafficking profile of the epidermal growth factor receptor.

@article{Mankouri2008TheHC,
  title={The hepatitis C virus non-structural protein NS5A alters the trafficking profile of the epidermal growth factor receptor.},
  author={Jamel Mankouri and Stephen Griffin and Mark Harris},
  journal={Traffic},
  year={2008},
  volume={9 9},
  pages={1497-509}
}
Hepatitis C virus (HCV) frequently establishes a persistent infection, leading to chronic liver disease. The NS5A protein has been implicated in this process as it modulates a variety of intracellular signalling pathways that control cell survival and proliferation. In particular, NS5A associates with several proteins involved in the endocytosis of the… CONTINUE READING