The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for function.

@article{Smith1998TheHB,
  title={The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for function.},
  author={G. Smith and J. Donello and R. L{\"u}ck and G. Steger and T. Hope},
  journal={Nucleic acids research},
  year={1998},
  volume={26 21},
  pages={
          4818-27
        }
}
Human Hepatitis B Virus (HBV) RNAs contain a cis -acting sequence, the post-transcriptional regulatory element (HPRE), which facilitates the cytoplasmic localization of intronless transcripts. Our previous studies have shown that the HPRE is composed of at least two independent sub-elements, HPREalpha and HPREbeta, which co-activate a reporter for RNA export in a greater than additive manner. Utilizing deletion, mutation and co-variational analyses, we have identified three regions important… Expand
35 Citations
Hepatitis B virus nuclear export elements: RNA stem-loop α and β, key parts of the HBV post-transcriptional regulatory element
  • 9
  • Highly Influenced
Solution structure of stem-loop α of the hepatitis B virus post-transcriptional regulatory element
  • 24
  • Highly Influenced
  • PDF
The hepatitis B virus PRE contains a splicing regulatory element
  • 37
  • PDF
Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors.
  • 202
...
1
2
3
4
...

References

SHOWING 1-10 OF 60 REFERENCES
Role of the hepatitis B virus posttranscriptional regulatory element in export of intronless transcripts.
  • 147
  • PDF
Hepatitis B virus transcript produced by RNA splicing.
  • 98
  • PDF
X-region-specific transcript in mammalian hepatitis B virus-infected liver.
  • 57
  • PDF
...
1
2
3
4
5
...