The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor.

@article{Nishizawa2000TheHV,
  title={The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor.},
  author={Mikio Nishizawa and Hajime Nakabayashi and Koji Kawai and Takashi Ito and Satoru Kawakami and Atsushi Nakagawa and Akira Niijima and Kenzo Uchida},
  journal={Journal of the autonomic nervous system},
  year={2000},
  volume={80 1-2},
  pages={14-21}
}
Glucagon-like peptide-1 (7-36)amide (tGLP-1), a representative humoral incretin, released into the portal circulation in response to a meal ingestion, exerts insulinotropic action through binding to the tGLP-1 receptor known to be a single molecular form thus far. We previously reported that the hepatic vagal nerve is receptive to intraportal tGLP-1, but not to non-insulinotropic full-length GLP-1-(1-37), through a mechanism mediated by specific receptor to the hormone. In the present study, we… CONTINUE READING