The hepatic response to thermal injury: is the liver important for postburn outcomes?

@article{Jeschke2009TheHR,
  title={The hepatic response to thermal injury: is the liver important for postburn outcomes?},
  author={Marc Gerhard Jeschke},
  journal={Molecular medicine},
  year={2009},
  volume={15 9-10},
  pages={
          337-51
        }
}
Thermal injury produces a profound hypermetabolic and hypercatabolic stress response characterized by increased endogenous glucose production via gluconeogenesis and glycogenolysis, lipolysis, and proteolysis. The liver is the central body organ involved in these metabolic responses. It is suggested that the liver, with its metabolic, inflammatory, immune, and acute phase functions, plays a pivotal role in patient survival and recovery by modulating multiple pathways following thermal injury… CONTINUE READING
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